{"id":51,"date":"2018-05-24T11:19:52","date_gmt":"2018-05-24T11:19:52","guid":{"rendered":"http:\/\/demo.athemes.com\/sydney-temp\/?page_id=4"},"modified":"2024-01-04T18:21:56","modified_gmt":"2024-01-04T18:21:56","slug":"my-front-page","status":"publish","type":"page","link":"https:\/\/www.thesinghlab.com\/","title":{"rendered":"Home"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"51\" class=\"elementor elementor-51\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-adfd994 elementor-section-full_width elementor-section-stretched elementor-section-height-default elementor-section-height-default\" data-id=\"adfd994\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-415d872\" data-id=\"415d872\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c28c82d premium-banner-responsive-yes elementor-widget elementor-widget-premium-addon-banner\" data-id=\"c28c82d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"premium-addon-banner.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"premium-banner-ib premium-banner-min-height premium-banner-animation1 none premium-banner__effect-type2\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"830\" height=\"166\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/12\/Picture1-830x166.png\" class=\"attachment-sydney-large-thumb size-sydney-large-thumb wp-image-1476\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/12\/Picture1-830x166.png 830w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/12\/Picture1-300x60.png 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/12\/Picture1-1024x205.png 1024w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/12\/Picture1-768x154.png 768w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/12\/Picture1-1536x308.png 1536w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/12\/Picture1-2048x410.png 2048w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/12\/Picture1-230x46.png 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/12\/Picture1-350x70.png 350w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/12\/Picture1-480x96.png 480w\" sizes=\"(max-width: 830px) 100vw, 830px\" \/>\t\t\t\t\t\t\t\t\t<div class=\"premium-banner-ib-desc\">\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h3 class=\"premium-banner-ib-title premium_banner_title\">\n\t\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default elementor-inline-editing pen\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"Type Here...\" style=\"text-transform: uppercase\">WELCOME TO THE SINGH LAB<\/span>\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"premium-banner-ib-content premium_banner_content\">\n\t\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-default elementor-inline-editing pen\" style=\"font-stretch: normal; text-transform: uppercase;\" padding-left: 100px\"<\/span>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e018a45 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e018a45\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2cf9782\" data-id=\"2cf9782\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3993f8c elementor-widget elementor-widget-image\" data-id=\"3993f8c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"654\" height=\"654\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/cereals-epigenomics-2.png\" class=\"attachment-medium_large size-medium_large wp-image-840\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/cereals-epigenomics-2.png 654w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/cereals-epigenomics-2-300x300.png 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/cereals-epigenomics-2-150x150.png 150w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/cereals-epigenomics-2-230x230.png 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/cereals-epigenomics-2-350x350.png 350w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/cereals-epigenomics-2-480x480.png 480w\" sizes=\"(max-width: 654px) 100vw, 654px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-e884e6c\" data-id=\"e884e6c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1ca7864 elementor-widget elementor-widget-heading\" data-id=\"1ca7864\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Cereals Epigenomics\u200b<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ba94186 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"ba94186\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e3ec59d elementor-widget elementor-widget-text-editor\" data-id=\"e3ec59d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #443f3f; font-family: Raleway, sans-serif; text-align: center; white-space: pre-wrap;\">Epigenetic modifications provide important clues regarding gene regulation mechanisms. For example, RNA-directed DNA methylation (RdDM) pathway targets many biological processes including silencing of transposable element and genome stability, plant development and reproduction, short and long-range signaling, and stress response (Erdmann and Picard 2020, PLOS Genetics, 16 (10): e1009034). In our previous studies, association of the key gene of RdDM, ARGONAUTE4_9 with plant reproductive process and seed dormancy (Singh et al. 2013, PLOS One, 8(10): e77009) prompted us to elucidate the role of RdDM in agronomically important traits such as Pre-Harvest Sprouting in small grain cereals. We are also investigating the miR-SPL (microRNA-SQUAMOSA promoter-binding protein-Like) module for its involvement in the developmental processes in cereals, such as barley (Tripathi et al., 2018 Scientific Reports 8:7085) and Brachypodium (Tripathi et al., 2020 Scientific Reports 10; 15302) and currently is the key component of our epigenetics research. <\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8603bae elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8603bae\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-74ce1d2\" data-id=\"74ce1d2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-56c9de1 elementor-widget elementor-widget-heading\" data-id=\"56c9de1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Genetic transformation and gene editing in functional genomics \u200b\u200b<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ab2c30b elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"ab2c30b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f2f1721 elementor-widget elementor-widget-text-editor\" data-id=\"f2f1721\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #443f3f; font-family: Raleway, sans-serif; text-align: center; white-space: pre-wrap;\">While the conventional breeding relied heavily on natural variations, the development of genetic transformation technologies provides an alternative approach in crop improvement. In the last few years, the emergence of gene editing technique became a major advance for site-directed mutagenesis first in animals, latter in plant species. We are one of the few labs worldwide working on cereal transformation and successfully developed oat and barley transformants tagged with Ac\/Ds transposons, overexpressing gene of interests or down-regulating target genes. More recently, we are using CRISPR-Cas9 system to perform gene editing in oat and barley to study economically important traits.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-78cfcf8\" data-id=\"78cfcf8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0f4c6e0 elementor-widget elementor-widget-image\" data-id=\"0f4c6e0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"476\" height=\"357\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/GENETIC-TRANSFORMATION-AND-GENE-EDITING-FOR-FUNCTIONAL-GENOMICS.png\" class=\"attachment-full size-full wp-image-844\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/GENETIC-TRANSFORMATION-AND-GENE-EDITING-FOR-FUNCTIONAL-GENOMICS.png 476w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/GENETIC-TRANSFORMATION-AND-GENE-EDITING-FOR-FUNCTIONAL-GENOMICS-300x225.png 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/GENETIC-TRANSFORMATION-AND-GENE-EDITING-FOR-FUNCTIONAL-GENOMICS-230x173.png 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/GENETIC-TRANSFORMATION-AND-GENE-EDITING-FOR-FUNCTIONAL-GENOMICS-350x263.png 350w\" sizes=\"(max-width: 476px) 100vw, 476px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-48cb6de elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"48cb6de\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-78e3d95\" data-id=\"78e3d95\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8c392ff elementor-widget elementor-widget-image\" data-id=\"8c392ff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"768\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/unnamed-3-1024x768.png\" class=\"attachment-large size-large wp-image-845\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/unnamed-3-1024x768.png 1024w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/unnamed-3-300x225.png 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/unnamed-3-768x576.png 768w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/unnamed-3-830x623.png 830w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/unnamed-3-230x173.png 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/unnamed-3-350x263.png 350w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/unnamed-3-480x360.png 480w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/03\/unnamed-3.png 1154w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-53776b9\" data-id=\"53776b9\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9b116e4 elementor-widget elementor-widget-heading\" data-id=\"9b116e4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">High quality &amp; nutritionally enhanced crops\u200b\u200b<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-850c013 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"850c013\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d706fb9 elementor-widget elementor-widget-text-editor\" data-id=\"d706fb9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #443f3f; font-family: Raleway, sans-serif; text-align: center; white-space: pre-wrap;\">We have been improving a variety of quality traits in cereal crops to meet the needs of different end users. For this purpose, we are exploring cysteine rich proteins (Thaumatin-Like Sweet Proteins), protein-carbohydrate interaction and redox regulation. We recently discovered a gene, HvTLP8 (thaumatin-like protein 8), redox-mediated controls the level of \u03b2-glucan in barley to enhance malt quality (Singh et al. 2017, PNAS, 114(29): 7725-7730). Meanwhile, we are targeting oil, starch, other nutritional traits in oat, barley, and field pea to add value to crop production. <\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3c9d9b1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3c9d9b1\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e953e9d\" data-id=\"e953e9d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8c00600 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"8c00600\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ba17047 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ba17047\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0e17cf6\" data-id=\"0e17cf6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ead9e93 elementor-widget elementor-widget-heading\" data-id=\"ead9e93\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">More resources<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9d14efe elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9d14efe\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-30620a2\" data-id=\"30620a2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d9805e8 elementor-align-right elementor-widget elementor-widget-button\" data-id=\"d9805e8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-lg\" href=\"https:\/\/www.thesinghlab.com\/?page_id=853\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">4 O'clock Forum<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-aa4209b\" data-id=\"aa4209b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ac500ee elementor-align-left elementor-widget elementor-widget-button\" data-id=\"ac500ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-lg\" href=\"https:\/\/www.thesinghlab.com\/?page_id=6\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Publications<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dea162a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dea162a\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-675e9dd\" data-id=\"675e9dd\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-376bfd1 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"376bfd1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-84e6e3d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"84e6e3d\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-865fd28\" data-id=\"865fd28\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dba935b elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"dba935b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;lightSpeedIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-xl\">Thank You<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4140885 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4140885\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f9575dc\" data-id=\"f9575dc\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-da4f64c elementor-widget elementor-widget-text-editor\" data-id=\"da4f64c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><span style=\"color: #443f3f; font-family: Raleway, sans-serif; text-align: center; white-space: pre-wrap;\">We would like to thank the following collaborators for their support.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dd37630 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dd37630\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-bad614c\" data-id=\"bad614c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5173ce6 elementor-invisible elementor-widget elementor-widget-image-gallery\" data-id=\"5173ce6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"image-gallery.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-image-gallery\">\n\t\t\t<div id='gallery-1' class='gallery galleryid-51 gallery-columns-4 gallery-size-medium'><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-slideshow=\"5173ce6\" data-elementor-lightbox-title=\"agrifood logo\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MTMwNywidXJsIjoiaHR0cHM6XC9cL3d3dy50aGVzaW5naGxhYi5jb21cL3dwLWNvbnRlbnRcL3VwbG9hZHNcLzIwMjNcLzA2XC9hZ3JpZm9vZC1sb2dvLmpwZyIsInNsaWRlc2hvdyI6IjUxNzNjZTYifQ%3D%3D\" href='https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/agrifood-logo.jpg'><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"141\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/agrifood-logo-300x141.jpg\" class=\"attachment-medium size-medium\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/agrifood-logo-300x141.jpg 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/agrifood-logo-230x108.jpg 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/agrifood-logo-350x165.jpg 350w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/agrifood-logo-480x226.jpg 480w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/agrifood-logo.jpg 637w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-slideshow=\"5173ce6\" data-elementor-lightbox-title=\"centre seve logo\" 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https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/centre-seve-logo.jpg 637w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-slideshow=\"5173ce6\" data-elementor-lightbox-title=\"Corteva logo\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MTMwOSwidXJsIjoiaHR0cHM6XC9cL3d3dy50aGVzaW5naGxhYi5jb21cL3dwLWNvbnRlbnRcL3VwbG9hZHNcLzIwMjNcLzA2XC9Db3J0ZXZhLWxvZ28uanBnIiwic2xpZGVzaG93IjoiNTE3M2NlNiJ9\" href='https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Corteva-logo.jpg'><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"141\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Corteva-logo-300x141.jpg\" class=\"attachment-medium size-medium\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Corteva-logo-300x141.jpg 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Corteva-logo-230x108.jpg 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Corteva-logo-350x165.jpg 350w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Corteva-logo-480x226.jpg 480w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Corteva-logo.jpg 637w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-slideshow=\"5173ce6\" data-elementor-lightbox-title=\"gefses logo\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MTMxMCwidXJsIjoiaHR0cHM6XC9cL3d3dy50aGVzaW5naGxhYi5jb21cL3dwLWNvbnRlbnRcL3VwbG9hZHNcLzIwMjNcLzA2XC9nZWZzZXMtbG9nby5qcGciLCJzbGlkZXNob3ciOiI1MTczY2U2In0%3D\" href='https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/gefses-logo.jpg'><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"141\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/gefses-logo-300x141.jpg\" class=\"attachment-medium size-medium\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/gefses-logo-300x141.jpg 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/gefses-logo-230x108.jpg 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/gefses-logo-350x165.jpg 350w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/gefses-logo-480x226.jpg 480w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/gefses-logo.jpg 637w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-slideshow=\"5173ce6\" data-elementor-lightbox-title=\"genome qc logo\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MTMxMSwidXJsIjoiaHR0cHM6XC9cL3d3dy50aGVzaW5naGxhYi5jb21cL3dwLWNvbnRlbnRcL3VwbG9hZHNcLzIwMjNcLzA2XC9nZW5vbWUtcWMtbG9nby5qcGciLCJzbGlkZXNob3ciOiI1MTczY2U2In0%3D\" href='https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/genome-qc-logo.jpg'><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"141\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/genome-qc-logo-300x141.jpg\" class=\"attachment-medium size-medium\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/genome-qc-logo-300x141.jpg 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/genome-qc-logo-230x108.jpg 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/genome-qc-logo-350x165.jpg 350w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/genome-qc-logo-480x226.jpg 480w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/genome-qc-logo.jpg 637w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-slideshow=\"5173ce6\" data-elementor-lightbox-title=\"NSERC logo\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MTMxMiwidXJsIjoiaHR0cHM6XC9cL3d3dy50aGVzaW5naGxhYi5jb21cL3dwLWNvbnRlbnRcL3VwbG9hZHNcLzIwMjNcLzA2XC9OU0VSQy1sb2dvLmpwZyIsInNsaWRlc2hvdyI6IjUxNzNjZTYifQ%3D%3D\" href='https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/NSERC-logo.jpg'><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"141\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/NSERC-logo-300x141.jpg\" class=\"attachment-medium size-medium\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/NSERC-logo-300x141.jpg 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/NSERC-logo-230x108.jpg 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/NSERC-logo-350x165.jpg 350w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/NSERC-logo-480x226.jpg 480w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/NSERC-logo.jpg 637w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-slideshow=\"5173ce6\" data-elementor-lightbox-title=\"prairie oat grower logo\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MTMxMywidXJsIjoiaHR0cHM6XC9cL3d3dy50aGVzaW5naGxhYi5jb21cL3dwLWNvbnRlbnRcL3VwbG9hZHNcLzIwMjNcLzA2XC9wcmFpcmllLW9hdC1ncm93ZXItbG9nby5qcGciLCJzbGlkZXNob3ciOiI1MTczY2U2In0%3D\" href='https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/prairie-oat-grower-logo.jpg'><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"141\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/prairie-oat-grower-logo-300x141.jpg\" class=\"attachment-medium size-medium\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/prairie-oat-grower-logo-300x141.jpg 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/prairie-oat-grower-logo-230x108.jpg 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/prairie-oat-grower-logo-350x165.jpg 350w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/prairie-oat-grower-logo-480x226.jpg 480w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/prairie-oat-grower-logo.jpg 637w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<a data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-slideshow=\"5173ce6\" data-elementor-lightbox-title=\"Sollio logo\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MTMxNCwidXJsIjoiaHR0cHM6XC9cL3d3dy50aGVzaW5naGxhYi5jb21cL3dwLWNvbnRlbnRcL3VwbG9hZHNcLzIwMjNcLzA2XC9Tb2xsaW8tbG9nby5qcGciLCJzbGlkZXNob3ciOiI1MTczY2U2In0%3D\" href='https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Sollio-logo.jpg'><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"141\" src=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Sollio-logo-300x141.jpg\" class=\"attachment-medium size-medium\" alt=\"\" srcset=\"https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Sollio-logo-300x141.jpg 300w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Sollio-logo-230x108.jpg 230w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Sollio-logo-350x165.jpg 350w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Sollio-logo-480x226.jpg 480w, https:\/\/www.thesinghlab.com\/wp-content\/uploads\/2023\/06\/Sollio-logo.jpg 637w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>\n\t\t\t<\/div><\/figure>\n\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>WELCOME TO THE SINGH LAB Cereals Epigenomics\u200b Epigenetic modifications provide important clues regarding gene regulation mechanisms. For example, RNA-directed DNA methylation (RdDM) pathway targets many biological processes including silencing of transposable element and genome stability, plant development and reproduction, short and long-range signaling, and stress response (Erdmann and Picard 2020, PLOS Genetics, 16 (10): e1009034). 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